Avidin provides a non-GLP acute and sub-chronic toxicology service on mice or rats. Traditional, as well as more complex toxicogenomical approach is also available.

A) Traditional pathological examination, LD50 determination in general or focused on organ-specific manifestations.

B) Toxicogenomics analysis of tissue- and organ-specific gene markers on nanocapillary HTS QRT-PCR panels. Expression of 56 genes are followed after in vivo administration of drugs in mouse liver heart, brain and kidney. Tissue-specific toxicity is predicted based on 1344 gene expression data.

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